She told Derek by buying a shirt for Zola that said "World's Best Big Sister". (A year of grieving will do that to you.) She was married to Derek Shepherd until his death; they have two daughters, Zola and Ellis, and a son, Bailey.
She is the daughter of the now-deceased Ellis Grey, a famed general surgeon, and the now-deceased Thatcher Grey.
Meredith found out she was pregnant three weeks into her pregnancy, a few months after Mark died. Now, showrunner Shonda Rhimes is hinting that "Grey's Anatomy" viewers have reason to worry about Meredith's baby. Ryan Seacrest’s sister, Meredith, welcomed a baby girl into the world on December 11, her brother told viewers of Live with Kelly and Ryan.Meredith … Meredith Grey is the head of general surgery at Grey Sloan Memorial Hospital. She has won a Catherine Fox Award. "She has that fall, and that starts a string of events that is cause for concern," Rhimes told TV Guide.
SPOILERS: On Grey's Anatomy Season 16, episode 9 it looks like Meredith and DeLuca might break up for good, plus do Alex and Jo adopt a baby left at the Station 19 firehouse? Of course as this is happening there are flashbacks of when Meredith had to call 911 on her own mother, as well as flashbacks of Ellis Grey giving up her daughter, Dr. Pierce, for adoption. Bailey Derek Shepherd is the only son of Meredith Grey and Derek Shepherd. So, now Grey's Anatomy has a wonderful new baby added to the show, and Meredith seems to be on the road to recovery. He has two siblings, an older sister, Zola, and a younger sister, Ellis.